Peptide Cleanup: Aspiration Mode v3.0. This application enables automated cleanup of from 1 to 96 peptide samples in a single run. This application aspirates the sample and wash solutions up through the cartridge resin bed rather than dispensing them through the resin bed, which is how the standard Peptide Cleanup application functions.

For most customers, Agilent recommends using the standard Peptide Cleanup application instead of the Peptide Cleanup: Aspiration Mode application. Although the two applications yield similar results, the standard Peptide Cleanup application is less sensitive to clogging and, therefore, more robust. However, some customers find the Peptide Cleanup: Aspiration Mode application provides slightly better purification.